Human Metapneumovirus (HMPV)

  • 06 Jan 2025

In News:

Five years after the COVID pandemic, China is experiencing a surge in HMPV cases, particularly in children under 14 years of age

Key Highlights:

  • What is HMPV?
    • A respiratory virus from the Pneumoviridae family, discovered in 2001.
    • Causes both upper and lower respiratory tract infections, similar to the common cold or flu.
  • Origin and Discovery:
    • Identified in the Netherlands in 2001 through genomic sequencing of respiratory samples.
  • Risk Groups:
    • Children under 5 years, especially infants.
    • Elderly individuals (65+).
    • Immunocompromised persons and those with chronic respiratory conditions (e.g., asthma).
  • Symptoms:
    • Common: Cough, runny nose, fever, sore throat.
    • Severe: Wheezing, shortness of breath, potentially leading to bronchitis or pneumonia.
  • Incubation Period: 3-6 days.
  • Transmission:
    • Spread via droplets from coughing or sneezing.
    • Close contact (e.g., handshakes, hugs).
    • Contaminated surfaces, touching face after contact.
  • Treatment:
    • No specific antiviral treatment or vaccine available.
    • Symptom management: hydration, rest, OTC medications for fever and congestion.
    • Severe cases may require hospitalization (oxygen therapy, IV fluids).
  • Diagnosis:
    • NAATs (Nucleic Acid Amplification Tests): Detect viral genetic material.
    • Antigen-based immunoassays: For severe cases or outbreaks.
  • Complications:
    • Can lead to bronchiolitis, bronchitis, pneumonia, asthma, or COPD flare-ups.
    • Risk of ear infections (otitis media) in some cases.
  • Prevention:
    • Hygiene: Regular handwashing, covering coughs/sneezes, maintaining personal hygiene.
    • Physical Distancing: Avoid close contact, wear masks in crowded settings.
    • Caution for Vulnerable Groups: Extra care for individuals with chronic respiratory conditions.

Global Situation:

  • China: Experiencing a rise in HMPV cases, particularly among children under 14 years.
  • India: No reported cases yet, but monitoring the situation closely.

Key Facts:

  • HMPV is a winter virus commonly seen in colder months (winter and early spring).
  • Estimated 10%-12% of respiratory illnesses in children are caused by HMPV.
  • The virus is part of the Pneumoviridae family, alongside respiratory syncytial virus (RSV), measles, and mumps.

No specific antiviral treatment or vaccine for HMPV; antibiotics are ineffective.