Chimaeras (The Hindu)

  • 21 Nov 2023

Why is it in the News?

In a recent landmark study, scientists reported successfully generating a live chimaera in non-human primates

About Chimaeras:

  • A genetic chimaera is a single organism made up of cells from more than one distinct genotype (or genetic makeup).
  • Examples of varying degrees of chimerism exist in the animal kingdom.
  • For instance, the half-sider budgerigar, a common pet parakeet, displays different colors on each side of its body due to chimerism.
  • In anglerfish, the male fuses with the female, eventually being absorbed, creating a single animal with a merged genetic makeup.
  • Marine sponges are known to have up to four distinct genotypes in one organism.
  • In humans, natural chimaeras occur when the genetic material in one cell changes, leading to a clonal population of cells different from the rest.
  • Fusion of two fertilized zygotes early in embryonic development can result in a condition where two genetic makeups coexist in a single individual.
  • Chimerism can also arise from twin or multiple pregnancies evolving into a single fetus or a twin fetus being absorbed into a singleton.